asprinAspirin is one of the most widely used over-the-counter medications but it may actually increase your risk of age related macular degeneration (AMD). Aspirin is used as an effective remedy for headaches, body aches and fever and by millions of people at high risk of heart attack due to atherosclerosis as a preventative measure, thanks to aspirin’s anticoagulant properties.

As part of The Beaver Dam Eye Study 5,000 participants (aged 43 to 86 years) were followed for more than 20 years and received eye examinations every five years with participants being asked if they had regularly used aspirin at least twice a week for more than three months. Researchers found that regular aspirin use 10 years prior to eye examination was associated with late AMD, with estimated incidence of 1.76 percent, compared to 1.03 percent in non-aspirin users. Researchers concluded that these associations, though small, were statistically significant. Regular aspirin use 10 years prior to eye examination was significantly associated with the “wet” form of AMD, which accounts for 10 percent of all AMD cases, but is responsible for the majority of catastrophic vision loss associated with the disease.

Another study from a 15-year Australian population-based group completed a questionnaire that assessed aspirin use, heart disease status and AMD risk factors. In addition, they received four eye examinations during the 15-year study period. Regular aspirin users developed wet AMD—an astounding 24.5 percent. Even after adjusting for other risk factors like age, sex, smoking, history of heart disease and body mass index, regular aspirin users still had a higher risk of developing wet AMD. Researchers concluded, “Regular aspirin use is associated with increased risk of incident neovascular [Wet] AMD, independent of history of cardiovascular disease and smoking.”

Alternatives to Aspirin

If you’re a regular aspirin user, you should get a thorough eye exam as soon as possible to determine your AMD status. This is extremely important because AMD often doesn’t show any symptoms until well after the condition has taken hold.

If you or someone you know has questions about the risk of age related macular degeneration (AMD) and taking aspirin, please call The Eye Clinic of Texas, an affiliate of Houston Eye Associates, at 800-423-3937, visit The Eye Clinic of Texas or facebook.com/ecot.lasik to schedule an appointment.

The Eye Clinic of Texas is an affiliate of Houston Eye Associates, the largest ophthalmology clinic in the nation. We are a leading eye care practice serving the greater Houston, Galveston, League City and Texas City with offices at 1100 Gulf Freeway, Suite 114, League City, Texas 77573, 7111 Medical Center Drive, Suite 110, Texas City, Texas 77590 and 2302 Avenue P, Galveston, Texas 77550.


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